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Article

Clonality of multifocal nonsmall cell lung cancer: implications for staging and therapy.

The European respiratory journal - 1 Jun 2012

Warth Arne, Macher-Goeppinger Stephan, Muley Thomas, Thomas Michael, Hoffmann Hans, Schnabel Philipp A, Penzel Roland, Schirmacher Peter, Aulmann Sebastian

Abstract excerpt

Nonsmall cell lung cancers (NSCLCs) display a variety of morphological and molecular features. Accurate subtyping of NSCLC has been shown to predict patient survival as well as response rates and toxicities of specific drugs. Assessment of multifocal lung tumours and the distinction of synchronous primary tumours from intrapulmonary metastases represent an important problem as this decision significantly...

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Identifiers

PMID: 22075483
DOI: 10.1183/09031936.00105911

Genes

EGFR
KRAS

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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