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Article

New aspects of the clinicopathology and genetic profile of metachronous multiple lung cancers.

Annals of surgery - 1 May 2014

Wu Chen-Tu, Lin Mong-Wei, Hsieh Min-Shu, Kuo Shuenn-Wen, Chang Yih-Leong

Abstract excerpt

OBJECTIVE: For treatment decisions and prognostic applications, we evaluated p53/epidermal growth factor receptor (EGFR) somatic aberrations in metachronous multiple lung cancers to differentiate multiple primary lung cancers (MPLCs) from pulmonary metastases. BACKGROUND: The current criteria to differentiate MPLCs from metastases are based on the histologic type and onset interval and do not incorporate genetic...

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PMID: 24368645
DOI: 10.1097/SLA.0000000000000385

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EGFR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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