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Article

LncRNA Dlx4os drives malignant transformation and phenotype switching in melanoma.

Epigenetics - 1 Dec 2026

Ayub Ana Luisa Pedroso, Tonin Beatriz Cristina Biz, Azevedo Hátylas, Jordão Pedro Henrique Fogaça, Saxena Tanvi, Sejour Leinal, Nsengimana Jeremie, Vlachos Ioannis, Reis Eduardo Moraes, Slack Frank John, Jasiulionis Miriam Galvonas

Abstract excerpt

Cutaneous melanoma, a highly aggressive and therapy-resistant skin cancer, is characterized by its remarkable cellular plasticity, enabling tumour cells to switch between different phenotypic states. This plasticity contributes to tumour heterogeneity and is regulated by key transcription factors. Long non-coding RNAs (lncRNAs) are emerging as crucial regulators in melanoma progression, yet much remains to be...

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Share to Cell Line, Tumor
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cell Transformation, Neoplastic

Share to Gene Expression Regulation, Neoplastic

Share to Homeodomain Proteins

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Share to RNA, Long Noncoding

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Identifiers

PMID: 41855479
DOI: 10.1080/15592294.2026.2641924
PMCID: PMC13003849

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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