Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic and Genomic Pathways of Melanoma Development, Invasion and Metastasis.

Genes - 28 Sept 2021

Motwani Jyoti, Eccles Michael R

Abstract excerpt

Melanoma is a serious form of skin cancer that accounts for 80% of skin cancer deaths. Recent studies have suggested that melanoma invasiveness is attributed to phenotype switching, which is a reversible type of cell behaviour with similarities to epithelial to mesenchymal transition. Phenotype switching in melanoma is reported to be independent of genetic alterations, whereas changes in gene transcription, and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Carcinogenesis
Share to Epigenesis, Genetic
Share to Gene Expression Regulation, Neoplastic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Heterogeneity

Share to Melanoma

Share to Mutation

Source

Open in PubMed Open full text

Identifiers

PMID: 34680938
DOI: 10.3390/genes12101543
PMCID: PMC8535311

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic and Genomic Pathways of Melanoma Development, Invasion and Metastasis.PMID 34680938Read ↗

Phenotype Switching and the Melanoma Microenvironment; Impact on Immunotherapy and Drug Resistance.Semantic proximity Read ↗

Cancer stem cells versus phenotype-switching in melanoma.Semantic proximity Read ↗

Molecular Susceptibility and Treatment Challenges in Melanoma.Semantic proximity Read ↗

Molecular, Genetic Susceptibility and Immunotherapy of MelanomaSemantic proximity Read ↗

Understanding Molecular Mechanisms of Phenotype Switching and Crosstalk with TME to Reveal New Vulnerabilities of Melanoma.Semantic proximity Read ↗

Cooperative behaviour and phenotype plasticity evolve during melanoma progression.Semantic proximity Read ↗

Phenotype Switching in Melanoma: Implications for Progression and TherapySemantic proximity Read ↗

Transcriptional signatures underlying dynamic phenotypic switching and novel disease biomarkers in a linear cellular model of melanoma progression.Semantic proximity Read ↗

Genomic and signalling pathway characterization of the NZM panel of melanoma cell lines: A valuable model for studying the impact of genetic diversity in melanoma.Semantic proximity Read ↗

Exploring the Complex and Multifaceted Interplay between Melanoma Cells and the Tumor MicroenvironmentSemantic proximity Read ↗

Heterogeneity in MelanomaSemantic proximity Read ↗

The genetics of malignant melanoma.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.