Article
A multiomics Mendelian randomization study on PANoptosis-related genes and gastric cancer risk.
The Journal of international medical research - 1 Mar 2026
Wang Yunliang, Xia Yujian, Weng Lin, Wang Jin, Meng Wenzi, Zhu Jiahui, Zhao Xin, Zhu Xinguo
Abstract excerpt
ObjectiveTo explore the potential involvement of PANoptosis-related genes in gastric cancer susceptibility through multiomics analyses.MethodsSummary-data-based Mendelian randomization was performed by integrating blood-derived methylation, gene expression, and protein quantitative trait loci data with genome-wide association study results. The findings were further evaluated in The Cancer Genome Atlas cohort,...
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