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Cathepsins and drug target genes in chronic gastritis: Deciphering potential therapeutic mechanisms via Mendelian randomization analysis

2026-06-23

Abstract excerpt

<title>Abstract</title> <p>Background Chronic gastritis is a highly prevalent gastrointestinal disorder characterized by persistent gastric mucosal inflammation. In approximately 10–30% of cases, this inflammation triggers a progression toward precancerous states, such as mucosal atrophy and intestinal metaplasia, which substantially increases the risk of gastric malignancy. Despite notable advances in diagnosti...

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Literature Corpus work
63e6e681-b169-5056-a3a6-85d4d31b2a06
DOI
10.21203/rs.3.rs-9701035/v1
Open publication

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