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Article

Identifying THBS3 as a potentially viable therapeutic target for gastric cancer: Intergration of Mendelian randomization and cell experiments validation study.

International journal of biological macromolecules - 1 May 2026

Wang Yuan-Yuan, Xing Yu-Tong, Guo Ke-Yu, Zhu Zhi-Tu

Abstract excerpt

Although targeted therapy significantly improves the prognosis of gastric cancer patients, the availability of cancer targeted drugs in clinical practice is still limited. In order to identify potential therapeutic targets for gastric cancer, Mendelian randomization (MR) analysis based on aggregated data was conducted. Specifically, cis eQTL data were obtained from the whole blood and gastric cohorts of GTEx...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 42067089
DOI: 10.1016/j.ijbiomac.2026.152278

Genes

THBS3
MVP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

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