Article
Hsp70s regulate circadian rhythm by interacting with PERIOD.
Cell communication and signaling : CCS - 12 Mar 2026
Zhao Xianguo, Lv Pengfei, Huang Yuansheng, Zhang Yifan, Wu Xiaoyu, Yang Xingzhuo, Du Juan
Abstract excerpt
Circadian rhythms synchronize life with the environment. Although the molecular feedback loop underlying these rhythms has been well-characterized, our understanding of cellular clocks remains incomplete. In this study, by applying cellular and biochemistry approaches, we reveal the involvement of Hsp70 family proteins in regulating the core clock feedback loop by modulating the condensation formation of the...
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