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Article

Multi-dimensional evidence establishing the causal association between metabolic syndrome and gout and the molecular mechanisms of comorbidity.

Frontiers in immunology - 1 Jan 2026

Li Jianbin, Zhang Jiamin, Li Suiran, Yao Xiaoge, Li Renhe, Liu Wei

Abstract excerpt

Objective: To systematically evaluate the causal association between metabolic syndrome (MetS) and its components with gout through integrated multi-dimensional methods, and reveal the genetic basis and transcriptomic characteristics of comorbidity. Methods: A three-phase research design was employed: (1) Real-world clinical cohort (n=8,853) was analyzed using propensity score matching (PSM), restricted cubic...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 41789074
DOI: 10.3389/fimmu.2026.1769138
PMCID: PMC12956786

Genes

FOS
JUN
TAP2
IFNGR1
PGAP3
SNX11

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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