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Article

Genetic Commonalities Between Metabolic Syndrome and Rheumatic Diseases Through Disease Interactome Modules.

Journal of cellular and molecular medicine - 1 Jan 2025

Shi Yinli, Guan Shuang, Liu Xi, Zhai Hongjun, Zhang Yingying, Liu Jun, Yang Weibin, Wang Zhong

Abstract excerpt

This study aims to elucidate the potential genetic commonalities between metabolic syndrome (MetS) and rheumatic diseases through a disease interactome network, according to publicly available large-scale genome-wide association studies (GWAS). The analysis included linkage disequilibrium score regression analysis, cross trait meta-analysis and colocalisation analysis to identify common genetic overlap. Using...

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Source

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Identifiers

PMID: 39789419
DOI: 10.1111/jcmm.70329
PMCID: PMC11717667

Genes

BAG6
GPSM3
PBX2
PRRC2A
PSMB8

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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