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Article

Genetic underpinning of the comorbidity between type 2 diabetes and osteoarthritis.

American journal of human genetics - 3 Aug 2023

Arruda Ana Luiza, Hartley April, Katsoula Georgia, Smith George Davey, Morris Andrew P, Zeggini Eleftheria

Abstract excerpt

Multimorbidity is a rising public health challenge with important implications for health management and policy. The most common multimorbidity pattern is the combination of cardiometabolic and osteoarticular diseases. Here, we study the genetic underpinning of the comorbidity between type 2 diabetes and osteoarthritis. We find genome-wide genetic correlation between the two diseases and robust evidence for...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 37433298
DOI: 10.1016/j.ajhg.2023.06.010
PMCID: PMC10432145

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