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Article

Role of Macrophage Socs3 in the Pathogenesis of Aortic Dissection.

Journal of the American Heart Association - 17 Jan 2018

Ohno-Urabe Satoko, Aoki Hiroki, Nishihara Michihide, Furusho Aya, Hirakata Saki, Nishida Norifumi, Ito Sohei, Hayashi Makiko, Yasukawa Hideo, Imaizumi Tsutomu, Akashi Hidetoshi, Tanaka Hiroyuki, Fukumoto Yoshihiro

Abstract excerpt

BACKGROUND: Aortic dissection (AD) is a life-threatening medical emergency caused by the abrupt destruction of the intimomedial layer of the aortic walls. Given that previous studies have reported the involvement of proinflammatory cytokine interleukin-6 in AD pathogenesis, we investigated the role of signal transduction and activator of transcription 3 signaling, a downstream pathway of interleukin-6 in...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 29343476
DOI: 10.1161/JAHA.117.007389
PMCID: PMC5850160

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