Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

LncRNA VINAS regulates atherosclerosis by modulating NF-κB and MAPK signaling

6 Oct 2020

Abstract excerpt

Long noncoding RNAs (lncRNAs) play important roles in regulating diverse cellular processes in the vessel wall, including atherosclerosis. RNA-Seq profiling of intimal lesions revealed a lncRNA, VINAS (Vascular INflammation and Atherosclerosis lncRNA Sequence), that is enriched in the aortic intima and regulates vascular inflammation. Aortic intimal expression of VINAS fell with atherosclerotic progression and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Atherosclerosis and Cardiovascular Diseases
Share to Cancer-related molecular mechanisms research
Share to Lipid metabolism and disorders

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 33021969
DOI: 10.1172/jci.insight.140627

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

LncRNA VINAS regulates atherosclerosis by modulating NF-κB and MAPK signalingPMID 33021969Read ↗

Coronary artery disease risk gene PRDM16 regulates smooth muscle homeostasis.Semantic proximity Read ↗

Coronary Artery Disease Risk Gene <i>PRDM16</i> is Preferentially Expressed in Vascular Smooth Muscle Cells and a Potential Novel Regulator of Smooth Muscle HomeostasisSemantic proximity Read ↗

The role of long noncoding RNA Nron in atherosclerosis development and plaque stabilitySemantic proximity Read ↗

<i>INKILN</i> is a novel long noncoding RNA promoting vascular smooth muscle inflammation via scaffolding MKL1 and USP10Semantic proximity Read ↗

CAV1 and VCL are Downregulated in Atherosclerotic Aortic EndothelialSemantic proximity Read ↗

LncRNA MALAT1 Promotes STAT3-Mediated Endothelial Inflammation by Counteracting the Function of miR-590.Semantic proximity Read ↗

ANGPTL4 stabilizes atherosclerotic plaques and modulates the phenotypic transition of vascular smooth muscle cells through KLF4 downregulation.Semantic proximity Read ↗

Krüppel-Like Factors in Vascular Inflammation: Mechanistic Insights and Therapeutic PotentialSemantic proximity Read ↗

LINC00341 exerts an anti-inflammatory effect on endothelial cells by repressing VCAM1Semantic proximity Read ↗

Regulation of Vascular Smooth Muscle Cell Dysfunction Under Diabetic Conditions by miR-504.Semantic proximity Read ↗

Identification of endoplasmic reticulum stress-associated lncRNAs influencing inflammation and VSMC function in abdominal aortic aneurysmSemantic proximity Read ↗

Atorvastatin inhibits inflammation through the cysteine-rich motor neuron 1 (Crim1) pathway in human umbilical vein endothelial cellsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.