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Article

Loss of EB2 delays mitotic progression in murine and human neural progenitors.

Development (Cambridge, England) - 1 Mar 2026

Phillips Alexander William, Cushion Thomas David, Vilceanu Alexandra, Heisterkamp Patrick, Keays David Anthony

Abstract excerpt

The construction of the human brain is dependent on neuronal progenitors that divide accurately generating billions of neurons. This neurogenic potential requires the efficient assembly of the mitotic spindle, which mediates the alignment of sister chromatids and their subsequent separation. The mitotic spindle is formed from microtubules, which are decorated with proteins that alter the functional repertoire of...

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Identifiers

PMID: 41725360
DOI: 10.1242/dev.204903

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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