Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A role for Ebi in neuronal cell cycle control.

The EMBO journal - 16 Oct 2000

Boulton S J, Brook A, Staehling-Hampton K, Heitzler P, Dyson N

Abstract excerpt

Mutations in ebi were isolated as enhancers of an over-proliferation phenotype generated by elevated E2F/DP activity in the Drosophila eye. ebi alleles also strongly suppress a phenotype caused by the cyclin-dependent kinase inhibitor p21, restoring S phases in the second mitotic wave of the developing eye disk. ebi mutant embryos display ectopic S phases within the peripheral nervous system and central nervous...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Suppression, Genetic
Share to Ubiquitins
Share to S Phase

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to GTP-Binding Proteins

Share to Insect Proteins

Share to Microscopy, Electron, Scanning

Share to Nervous System

Source

Open in PubMed Open full text

Identifiers

PMID: 11032805
DOI: 10.1093/emboj/19.20.5376
PMCID: PMC314025

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A role for Ebi in neuronal cell cycle control.PMID 11032805Read ↗

E Proteins and Id2 Converge on p57<sup>Kip2</sup> To Regulate Cell Cycle in Neural CellsSemantic proximity Read ↗

Loss of EB2 delays mitotic progression in murine and human neural progenitors.Semantic proximity Read ↗

Cell‐context specific role of the E2F/Rb pathway in development and diseaseSemantic proximity Read ↗

MEIS2 is essential for neuroblastoma cell survival and proliferation by transcriptional control of M-phase progressionSemantic proximity Read ↗

RB, the conductor that orchestrates life, death and differentiation.Semantic proximity Read ↗

Ectopic expression of dE2F and dDP induces cell proliferation and death in the Drosophila eye.Semantic proximity Read ↗

Mitosis in neurons: Roughex and APC/C maintain cell cycle exit to prevent cytokinetic and axonal defects in Drosophila photoreceptor neurons.Semantic proximity Read ↗

Upregulation of Mitimere and Nubbin acts through cyclin E to confer self-renewing asymmetric division potential to neural precursor cells.Semantic proximity Read ↗

S phase-coupled E2f1 destruction ensures homeostasis in proliferating tissues.Semantic proximity Read ↗

dDP is needed for normal cell proliferation.Semantic proximity Read ↗

Cell cycle-dependent cues regulate temporal patterning of the <i>Drosophila</i> central brain neural stem cellsSemantic proximity Read ↗

Coordinating cell proliferation and differentiation: Antagonism between cell cycle regulators and cell type-specific gene expression.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.