Article
Molecular Profiling Reveals Involvement of ESCO2 in Intermediate Progenitor Cell Maintenance in the Developing Mouse Cortex.
Stem cell reports - 13 Apr 2021
Ulmke Pauline Antonie, Sakib M Sadman, Ditte Peter, Sokpor Godwin, Kerimoglu Cemil, Pham Linh, Xie Yuanbin, Mao Xiaoyi, Rosenbusch Joachim, Teichmann Ulrike, Nguyen Huu Phuc, Fischer Andre, Eichele Gregor, Staiger Jochen F, Tuoc Tran
Abstract excerpt
Intermediate progenitor cells (IPCs) are neocortical neuronal precursors. Although IPCs play crucial roles in corticogenesis, their molecular features remain largely unknown. In this study, we aimed to characterize the molecular profile of IPCs. We isolated TBR2-positive (+) IPCs and TBR2-negative (-) cell populations in the developing mouse cortex. Comparative genome-wide gene expression analysis of TBR2+ IPCs...
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