Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Immune cell dynamics and mechanisms of epithelial injury in celiac disease.

Frontiers in immunology - 1 Jan 2026

Marafini Irene, Salvatori Silvia, Troncone Edoardo, De Vico Pasquale, De Cristofaro Elena, Monteleone Giovanni

Abstract excerpt

Despite continuous exposure to dietary and microbial antigens, the intestinal mucosa maintains a delicate balance between immune activation and tolerance. This equilibrium depends on the integrity and regulatory functions of the intestinal epithelium and associated immune cells. In the case of celiac disease (CD), gluten ingestion disturbs this equilibrium in people with a genetic predisposition (those with...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Celiac Disease
Share to Gliadin
Share to Glutens

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to GTP-Binding Proteins

Share to HLA-DQ Antigens

Share to Intestinal Mucosa

Share to Protein Glutamine gamma Glutamyltransferase 2

Share to Transglutaminases

Source

Open in PubMed Open full text

Identifiers

PMID: 41694349
DOI: 10.3389/fimmu.2026.1766513
PMCID: PMC12894275

Genes

CD4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Immune cell dynamics and mechanisms of epithelial injury in celiac disease.PMID 41694349Read ↗

Gene-Environment Interactions in Celiac Disease: The Role of the Intestinal Epithelium.Semantic proximity Read ↗

Local communication among mucosal immune cells in patients with celiac disease.Semantic proximity Read ↗

Pathophysiology and immunogenetics of celiac disease.Semantic proximity Read ↗

Interplay Between Gluten, HLA, Innate and Adaptive Immunity Orchestrates the Development of Coeliac DiseaseSemantic proximity Read ↗

Intestinal epithelium, intraepithelial lymphocytes and the gut microbiota - Key players in the pathogenesis of celiac diseaseSemantic proximity Read ↗

Celiac disease: an immunological jigsaw.Semantic proximity Read ↗

An updated overview on celiac disease: from immuno-pathogenesis and immuno-genetics to therapeutic implications.Semantic proximity Read ↗

Co-factors, Microbes, and Immunogenetics in Celiac Disease to Guide Novel Approaches for Diagnosis and Treatment.Semantic proximity Read ↗

From Autoimmunity to Intestinal Tissue Damage: Insights From Potential Celiac Disease as a Paradigm of Disease Progression.Semantic proximity Read ↗

Celiac disease: sandwiched between innate and adaptive immune responses induced by gluten.Semantic proximity Read ↗

Distinct and Synergistic Contributions of Epithelial Stress and Adaptive Immunity to Functions of Intraepithelial Killer Cells and Active Celiac Disease.Semantic proximity Read ↗

“Coelionomics”: towards understanding the molecular pathology of coeliac diseaseSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.