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Article

Celiac disease: an immunological jigsaw.

Immunity - 29 Jun 2012

Meresse Bertrand, Malamut Georgia, Cerf-Bensussan Nadine

Abstract excerpt

Celiac disease (CD) is a chronic enteropathy induced by dietary gluten in genetically predisposed people. The keystone of CD pathogenesis is an adaptive immune response orchestrated by the interplay between gluten and MHC class II HLA-DQ2 and DQ8 molecules. Yet, other factors that impair immunoregulatory mechanisms and/or activate the large population of intestinal intraepithelial lymphocytes (IEL) are...

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Identifiers

PMID: 22749351
DOI: 10.1016/j.immuni.2012.06.006

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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