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Article

From Autoimmunity to Intestinal Tissue Damage: Insights From Potential Celiac Disease as a Paradigm of Disease Progression.

Gastroenterology - 1 Jul 2026

Mandile Roberta, Discepolo Valentina, Auricchio Renata, Troncone Riccardo

Abstract excerpt

Immune-mediated inflammatory diseases are undergoing a paradigm shift from treatment of established pathology toward prevention in at-risk individuals. Celiac disease (CeD), driven by an aberrant immune response to dietary gluten in genetically predisposed individuals, represents an ideal model to investigate the transition from tolerance to autoimmunity. Within this framework, potential celiac disease...

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Identifiers

PMID: 41881136
DOI: 10.1053/j.gastro.2026.03.005

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