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Article

Pathophysiology and immunogenetics of celiac disease.

Clinica chimica acta; international journal of clinical chemistry - 1 Mar 2022

Aboulaghras Sara, Piancatelli Daniela, Oumhani Khadija, Balahbib Abdelaali, Bouyahya Abdelhakim, Taghzouti Khalid

Abstract excerpt

Celiac disease (CD) is a chronic inflammatory enteropathy caused by gluten (protein from wheat, rye and, barley) in genetically predisposed individuals carrying the HLA-DQ2/HLA-DQ8 genotype. This pathology has a multifactorial etiology in which HLA genes, the microbiome, gluten and, other environmental factors are involved in the development of the disease. Its pathogenesis involves both innate and adaptive...

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Identifiers

PMID: 35120899
DOI: 10.1016/j.cca.2022.01.022

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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