Fine Mapping of MHC Region Identifies Novel Susceptibility Loci in Multiple Myeloma When Comparing With Its Precursor Monoclonal Gammopathy of Unknown Significance.

Abstract excerpt

Genome-wide association studies have linked major histocompatibility complex (MHC) region loci to immune-related diseases, but their role in multiple myeloma (MM) progression from monoclonal gammopathy of undetermined significance (MGUS) remains unclear. This case-control study included 238 individuals with MGUS (> 5 years follow-up without MM progression) and 618 MM patients from MCW Froedtert Hospital...

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