Epidemiology, genetics and treatment of multiple myeloma and precursor diseases.

doi:10.1002/ijc.33762

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Back to search

Article

Epidemiology, genetics and treatment of multiple myeloma and precursor diseases.

International journal of cancer - 15 Dec 2021

Hemminki Kari, Försti Asta, Houlston Richard, Sud Amit

Abstract excerpt

Multiple myeloma (MM) is a hematological malignancy caused by the clonal expansion of plasma cells. The incidence of MM worldwide is increasing with greater than 140 000 people being diagnosed with MM per year. Whereas 5-year survival after a diagnosis of MM has improved from 28% in 1975 to 56% in 2012, the disease remains essentially incurable. In this review, we summarize our current understanding of MM...

Topics

Biomarkers, Tumor
Cyclin D1
Exosome Multienzyme Ribonuclease Complex
Genetic Predisposition to Disease
Histone Demethylases
Humans
Immunotherapy
Multiple Myeloma
Mutation
Plasma Cells
Repressor Proteins
Risk Factors
Survival Rate
Transcriptional Elongation Factors

Source

Open in PubMed Open full text

Identifiers

PMID: 34398972
DOI: 10.1002/ijc.33762
PMCID: PMC11497332

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics