Article

Exploring the Molecular Mechanisms and Shared Genetic Characteristics of Monoclonal Gammopathy of Undetermined Significance and Multiple Myeloma

2024-08-10

Abstract excerpt

<title>Abstract</title> <p>Monoclonal gammopathy of undetermined significance (MGUS) serves as a precursor to multiple myeloma (MM), with a subset of MGUS cases advancing to MM each year. Despite extensive research, the mechanisms driving this progression are not yet fully understood. Leveraging transcriptomic data from the Gene Expression Omnibus (GEO) database, this study conducted an analysis of differentially...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 79a0186d-7891-5edc-a573-acd25144d8e7
DOI: 10.21203/rs.3.rs-4701045/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Exploring the Molecular Mechanisms and Shared Genetic Characteristics of Monoclonal Gammopathy of Undetermined Significance and Multiple MyelomaDOI 10.21203/rs.3.rs-4701045/v1Read

A Comprehensive Review of the Genomics of Multiple Myeloma: Evolutionary Trajectories, Gene Expression Profiling, and Emerging Therapeutics.Semantic proximity Read

Monoclonal Gammopathy of Undetermined Significance: Current Concepts and Future Prospects.Semantic proximity Read

Genome-Wide Identification of Potential Biomarkers in Multiple Myeloma Using Meta-Analysis of mRNA and miRNA Expression DataSemantic proximity Read

Genotype-immunophenotype analysis reveals the immunogenomic subtype and prognosis of multiple myeloma.Semantic proximity Read

Mapping the Molecular Terrain of Multiple Myeloma: A Focus on Inflammation-Driven PathwaysSemantic proximity Read

Predictive potential of cuproptosis-related genes in multiple myeloma: Comprehensive analysis based on bone marrow whole-genome sequencingSemantic proximity Read

Epidemiology, genetics and treatment of multiple myeloma and precursor diseases.Semantic proximity Read

Gene-expression signature of benign monoclonal gammopathy evident in multiple myeloma is linked to good prognosisSemantic proximity Read

A Comprehensive Targeted Panel of 295 Genes: Unveiling Key Disease Initiating and Transformative Biomarkers in Multiple MyelomaSemantic proximity Read

Identification of a novel cuproptosis‐related gene signature for multiple myeloma diagnosisSemantic proximity Read

Identification of mutation gene prognostic biomarker in multiple myeloma through gene panel exome sequencing and transcriptome analysis in Chinese population.Semantic proximity Read

Fine Mapping of MHC Region Identifies Novel Susceptibility Loci in Multiple Myeloma When Comparing With Its Precursor Monoclonal Gammopathy of Unknown Significance.Semantic proximity Read