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Article

Distinct epigenetic aging in sporadic and hereditary neuroendocrine neoplasms.

Clinical epigenetics - 9 Feb 2026

Weinstein Shiri, Halperin Reut, Tirosh Amit

Abstract excerpt

BACKGROUND: Epigenetic clocks assess DNA aging based on DNA methylation. We aimed to study the utility of methylation clocks in understanding the distinct characteristics of sporadic and hereditary neuroendocrine neoplasms (NEN). METHODS: Epigenetic age and acceleration were calculated based on Horvath multi-tissue, Levine, and Hannum clocks, and compared by genetic predisposition and NEN grading (WHO-defined G1,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 41656300
DOI: 10.1186/s13148-026-02069-1
PMCID: PMC12983614

Genes

VHL
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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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