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Article

Role of Specific miRNA Expression and Nuclear Kappa B Gene Polymorphism as Potential Diagnostic Markers for Chronic Myeloid Leukemia.

Medical principles and practice : international journal of the Kuwait University, Health Science Centre - 1 Jan 2026

Alhmoud Jehad F, Alqaraleh Moath, Dala-Ali Sarah N, Alhiary Leen S, Dababneh Issa I, Odeh Nada L, Elzogheir Nirmeen, Alqudah Dana A, Al-Rawashde Futoon Abedrabbu

Abstract excerpt

<p>Objective: This study assesses microRNA-21 (miR-21) and microRNA-302 (miR-302) levels and examines their association with a nuclear factor kappa-light-chain enhancer of activated B cells (NF-κB) gene single nucleotide polymorphism (SNP) in chronic myeloid leukemia (CML) patients, aiming to identify these miRNAs as potential diagnostic biomarkers. The findings could contribute to improved diagnostic and...

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Identifiers

PMID: 41615870
DOI: 10.1159/000550722
PMCID: PMC13065331

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