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Article

Prognostic Significance of miR-181a and miR-181b Expression and NPM1 Mutations in Patients With Acute Myeloid Leukemia Undergoing Hematopoietic Stem Cell Transplant.

Experimental and clinical transplantation : official journal of the Middle East Society for Organ Transplantation - 1 Apr 2026

Saadi Mahdiyar Iravani, Noshadi Nasrin, Ramzi Mani, Karimi Zahed, Yaghobi Ramin, Parand Shirin

Abstract excerpt

OBJECTIVES: MicroRNAs play an essential role in acute myeloid leukemia pathogenesis, including cell survival, differentiation, and proliferation. We aimed to examine miR -181a and miR -181b expression levels in patients with recently diagnosed acute myeloid leukemia, focusing on those who developed acute graft -versus -host disease, and to characterize NPM 1 mutations present in these patients. MATERIALS AND...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 42126039
DOI: 10.6002/ect.2025.0309

Genes

NPM1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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