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Article

microRNA expression profiling as supportive diagnostic and therapy prediction tool in chronic myeloid leukemia

1 Jan 2015

Abstract excerpt

Chronic myeloid leukemia (CML) is a myeloproliferative disorder of hematopoietic stem cells carrying Philadelphia (Ph) chromosome and the oncogenic BCR-ABL1 fusion gene. microRNAs (miRNAs) belong to hematopoiesis transcription regulators and their deregulated expression associates with pathogenesis of CML. The current study assesses and validates expression profiles of selected oncogenic and tumor suppressing...

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PMID: 26458312
DOI: 10.4149/neo_2015_115

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