Article

Dysregulation of MicroRNA-181a-5p Targets TNFAIP3 to Promote MIF-CXCR4 Signaling and Immune Inflammatory Remodeling in Chronic Myeloid Leukemia

2025-12-26

Abstract excerpt

<h4>Background: </h4> The non-coding RNAs, particularly microRNA-181a-5p target the expression of tumor necrosis factor alpha-induced protein 3 (TNFAIP3) a key negative regulator of NF-κB signaling and affect the levels of macrophage migration inhibitory factor (MIF) and chemokine receptor type 4 (CXCR4) in chronic myeloid leukamia (CML). Methods The study included 57 individuals with chronic myeloid leukemia (CML...

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Literature Corpus work: 1d405934-2078-581d-9013-5d277813e27f
DOI: 10.12688/f1000research.172236.1

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