Article
The rs61764370 Functional Variant in the KRAS Oncogene is Associated with Chronic Myeloid Leukemia Risk in Women.
Asian Pacific journal of cancer prevention : APJCP - 1 Jan 2016
Gutiérrez-Malacatt Humberto, Ayala-Sanchez Manuel, Aquino-Ortega Xochitl, Dominguez-Rodriguez Jacqueline, Martinez-Tovar Adolfo, Olarte-Carrillo Irma, Martinez-Hernandez Angelica, C Cecilia Contreras-Cubas, Orozco Lorena, Cordova Emilio J
Abstract excerpt
BACKGROUND: Chronic myeloid leukemia (CML) is one of the most frequent hematopoietic malignancies in the elderly population; however, knowledge is limited regarding the genetic factors associated with increased risk for CML. Polymorphisms affecting microRNA (miRNA) biogenesis or mRNA:miRNA interactions are important risk factors in the development of different types of cancer. Thus, we carried out a case-control...
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