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Dysregulation of MicroRNA-181a-5p Targets TNFAIP3 to Promote MIF-CXCR4 Signaling and Immune Inflammatory Remodeling in Chronic Myeloid Leukemia

2026-03-26

Abstract excerpt

<h4>Background: </h4> The non-coding RNAs, particularly microRNA-181a-5p target the expression of tumor necrosis factor alpha-induced protein 3 (TNFAIP3) a key negative regulator of NF-κB signaling and affect the levels of macrophage migration inhibitory factor (MIF) and chemokine receptor type 4 (CXCR4) in chronic myeloid leukamia (CML). Methods The study included 57 individuals with chronic myeloid leukemia (CML...

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Literature Corpus work
55ac9286-5f76-5a78-b7a2-14245c1a5b28
DOI
10.12688/f1000research.172236.3
Open publication

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Dysregulation of MicroRNA-181a-5p Targets TNFAIP3 to Promote MIF-CXCR4 Signaling and Immune Inflammatory Remodeling in Chronic Myeloid LeukemiaDOI 10.12688/f1000research.172236.3
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