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Article

Identification of candidate genes associated with mitotic-origin aneuploidy: a genome-wide association study.

Journal of assisted reproduction and genetics - 1 Apr 2026

Lyu Zhengxin, An Jianting, Song Shi, Zhu Xiaohui, Yan Liying, Yuan Peng, Yan Zhiqiang, Qiao Jie

Abstract excerpt

PURPOSE: Aneuploidy is the most common genetic abnormality in human embryos and is one of the leading causes of embryo transfer failure. We aimed to identify candidate genes linked to mitotic-origin aneuploidy. METHODS: A control group of 588 euploid embryos and a case group of 236 mosaic embryos were utilized. Sequence alignment was first conducted to identify single nucleotide polymorphism (SNP) loci. Quality...

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Identifiers

PMID: 41591667
DOI: 10.1007/s10815-026-03810-8
PMCID: PMC13103094

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EMP2

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