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Article

Phosphoregulation of RAD51AP1 function in homology-directed repair.

The Journal of biological chemistry - 1 Mar 2026

Sharma Neelam, Uhrig Mollie E, Kwon Youngho, Sung Patrick, Wiese Claudia

Abstract excerpt

Homology-directed DNA repair (HDR) is critical for genome stability and tumor suppression. HDR is initiated by the RAD51 single-stranded (ss)DNA nucleoprotein filament, which conducts the homology search and invades a homologous DNA template, creating a displacement-loop (D-loop). The RAD51 filament is assisted in these processes by several proteins. One such protein is RAD51-associated protein 1 (RAD51AP1),...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 41534830
DOI: 10.1016/j.jbc.2026.111149
PMCID: PMC12887393

Genes

RAD51AP1
RAD51
CDK2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 17 Oct 2026.

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