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Article

Homology-driven chromatin remodeling by human RAD54.

Nature structural & molecular biology - 1 May 2007

Zhang Zhaoqing, Fan Hua-Ying, Goldman Joseph A, Kingston Robert E

Abstract excerpt

Human RAD51 and RAD54 are key players in homologous recombination, a process that requires homology recognition and strand invasion by a RAD51-single-stranded DNA (ssDNA) nucleoprotein filament and chromatin remodeling by RAD54. Here we use in vitro chromatin reconstitution systems to show that RAD51-ssDNA stimulates RAD54-dependent chromatin remodeling in a homology-dependent, polarity-independent manner. This...

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Identifiers

PMID: 17417655
DOI: 10.1038/nsmb1223

Genes

RAD51

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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