Article
RAD-ical New Insights into RAD51 Regulation
2018-11-22
Abstract excerpt
Accurate repair of DNA is critical for genome stability and cancer prevention. DNA double-strand breaks are one of the most toxic lesions and can be repaired using homologous recombination (HR). HR is a high-fidelity DNA repair pathway that uses a homologous template for repair. One central HR step is RAD51 nucleoprotein filament formation on the single-stranded DNA ends, a step required for the homology search an...
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Identifiers and source
- Literature Corpus work
- 5fc69ffc-46d3-5bd9-a131-cbf5ded8f770
- DOI
- 10.20944/preprints201811.0541.v1