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Article

Oncologic Outcomes by Pathogenic BRCA Mutation Status in Young Luminal Breast Cancer: A Propensity-Matched Cohort.

JCO precision oncology - 1 Jan 2026

Park Woong Ki, Nam Seok Jin, Kim Seok Won, Lee Jeong Eon, Yu Jonghan, Lee Se Kyung, Ryu Jai Min, Ahn Jin Seok, Park Yeon Hee, Kim Ji-Yeon, Chae Byung Joo

Abstract excerpt

PURPOSE: Young patients with estrogen receptor (ER)-positive, human epidermal growth factor receptor 2 (HER2)-negative tumors often exhibit poor outcomes. This study evaluated whether BRCA mutation contributes to prognosis by comparing oncologic outcomes according to BRCA status. MATERIALS AND METHODS: We conducted a retrospective study of a prospective institutional cohort. Among 1,025 patients 40 years and...

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Identifiers

PMID: 41533992
DOI: 10.1200/PO-25-00445

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BRCA1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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