Article
Clinical outcome of triple negative breast cancer in BRCA1 mutation carriers and noncarriers.
Cancer - 15 Jul 2011
Lee Larissa J, Alexander Brian, Schnitt Stuart J, Comander Amy, Gallagher Bridget, Garber Judy E, Tung Nadine
Abstract excerpt
BACKGROUND: Women with BRCA1 mutations develop breast cancer with similar pathologic features to sporadic triple negative (TN) breast cancer, a subtype associated with early disease relapse and poor outcome. The clinical outcome of women with and without BRCA1 mutations who had TN breast cancer treated with conventional chemotherapy were compared. METHODS: Women with stage I to III TN breast cancer who had BRCA1...
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