Article
A matched case-control study of the prognosis of early breast cancer in patients with Li-Fraumeni syndrome (BREAST TP53).
Breast (Edinburgh, Scotland) - 1 Apr 2023
Petry Vanessa, Bonadio Renata Colombo, Testa Laura, Cohn Daniela Jbh, Cagnacci Allyne, Campos Roberta G, Fragoso Maria Cândida Bv, Estevez-Diz Maria Del Pilar
Abstract excerpt
INTRODUCTION: Breast cancer (BC) is the most common type of cancer in premenopausal women with germline TP53 pathogenic variants (mTP53) (Li Fraumeni syndrome - LFS). However, little is known about the BC prognosis in these patients. This study analyzed the BC-related oncologic outcomes of patients with LFS. METHODS: We evaluated a cohort of LFS patients with BC in comparison with a control cohort of BC patients...
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