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Multi-omics and molecular testing: A new insight into the genetic mechanisms of sarcopenia and arthritis.

Clinical and experimental medicine - 14 Jan 2026

Wang Zhonghai, Yu Meiling, Wang Han

Abstract excerpt

Sarcopenia and arthritis, characterized by age-related progressive loss of skeletal muscle mass and function, profoundly impact the well-being of older adults. Our study endeavors to explore the unclear genetic structure between them. Using advanced statistical genetic approaches and genome-wide association study (GWAS) summary statistics, we explored the shared genetic basis among multiple manifestations of...

Topics

Humans
Sarcopenia
Genome-Wide Association Study
Multiomics
Arthritis
Genetic Predisposition to Disease
Polymorphism, Single Nucleotide
Gene Expression Profiling

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 41530564
DOI: 10.1007/s10238-025-01985-5
PMCID: PMC12819441

Genes

DNAJC27
GDF5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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