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Article

Proteomic and Genetic Insights into Ancestry-Specific Associations in Parkinson's Disease.

Movement disorders : official journal of the Movement Disorder Society - 1 Apr 2026

Lim Amanda Wei-Yin, Foo Jia-Nee, Chew Elaine Guo-Yan, Lim Shen-Yang, Tan Ai Huey, Hwang Liang-Dar, MacGregor Stuart, Rentería Miguel E, Ong Jue-Sheng

Abstract excerpt

BACKGROUND: Although genome-wide association studies (GWAS) have identified numerous common genetic risk variants for Parkinson's disease (PD), the underlying biological mechanisms remain largely unresolved. OBJECTIVES: We aimed to identify circulating proteins causally associated with PD risk in European and East Asian populations and determine whether these associations are shared or ancestry-specific. METHODS:...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 41504309
DOI: 10.1002/mds.70169

Genes

BST1
PM20D1
TXNDC15

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 9 Sept 2026.

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