Back to search

Article

Assessment of common genetic variation in Alzheimer’s and Parkinson’s diseases reveals global distinction in population attributable risk

2024-09-24

Abstract excerpt

Emerging evidence suggests that the genetic architecture of Alzheimer’s (AD) and Parkinson’s diseases (PD) risk varies across ancestries. This study seeks to explore distinct and universal genetic targets across individuals of Latino, African/African Admixed, East Asian, and European populations by implementing Population Attributable Risk (PAR) comparisons on summary statistics from genome-wide association studie...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
a8984718-4972-5f2d-a5fa-b8feb0140af9
DOI
10.1101/2024.09.23.24314240
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Assessment of common genetic variation in Alzheimer’s and Parkinson’s diseases reveals global distinction in population attributable riskDOI 10.1101/2024.09.23.24314240
Biobank-scale characterization of Alzheimer’s disease and related dementias identifies potential disease-causing variants, risk factors, and genetic modifiers across diverse ancestriesSemantic proximity
Novel Parkinson’s Disease Genetic Risk Factors Within and Across European PopulationsSemantic proximity
The Global Landscape of Genetic Variation in Parkinson’s disease: Multi-Ancestry Insights into Established Disease Genes and their Translational RelevanceSemantic proximity
Deciphering the Genetic Architecture of Parkinson’s Disease in IndiaSemantic proximity
Insights into Ancestral Diversity in Parkinson’s Disease Risk: A Comparative Assessment of Polygenic Risk ScoresSemantic proximity
Genome-wide Association Identifies Novel Etiological Insights Associated with Parkinson’s Disease in African and African Admixed PopulationsSemantic proximity
A multi-ancestry polygenic risk score for Alzheimer disease is associated with cognitive decline, hippocampal atrophy and neuropathological hallmarks in diverse populationsSemantic proximity
Large-scale genetic characterization of Parkinson’s disease in the African and African admixed populationsSemantic proximity
Cross-ancestry performance of Parkinson’s disease polygenic risk scores in admixed Latin American populationsSemantic proximity
Genotype-phenotype association study conducted on LARGE-PD reveals novel loci associated with Parkinson’s DiseaseSemantic proximity
The genetic architecture of Parkinson disease in Spain: characterizing population-specific risk, differential haplotype structures, and providing etiologic insightSemantic proximity
Identification of genetic risk loci and causal insights associated with Parkinson's disease in African and African admixed populations: a genome-wide association study.Semantic proximity
Select a neighboring publication to make it the new centre.