Article
Multi-ancestry genome-wide association meta-analysis of Parkinson's disease.
Nature genetics - 1 Jan 2024
Kim Jonggeol Jeffrey, Vitale Dan, Otani Diego Véliz, Lian Michelle Mulan, Heilbron Karl, Iwaki Hirotaka, Lake Julie, Solsberg Caroline Warly, Leonard Hampton, Makarious Mary B, Tan Eng-King, Singleton Andrew B, Bandres-Ciga Sara, Noyce Alastair J, Blauwendraat Cornelis, Nalls Mike A, Foo Jia Nee, Mata Ignacio
Abstract excerpt
Although over 90 independent risk variants have been identified for Parkinson's disease using genome-wide association studies, most studies have been performed in just one population at a time. Here we performed a large-scale multi-ancestry meta-analysis of Parkinson's disease with 49,049 cases, 18,785 proxy cases and 2,458,063 controls including individuals of European, East Asian, Latin American and African...
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