Article

Sex-Stratified Multi-Omics Identifies Sexually Dimorphic Molecular Targets in Parkinson’s Disease

2026-04-10

Abstract excerpt

Parkinson’s disease (PD) exhibits well-established sex differences in prevalence and clinical phenotypes, yet the underlying molecular mechanisms remain largely elusive. Here, we conducted a comprehensive sex-stratified multi-omic integration to identify sex-specific causal proteins and biological pathways in PD. We performed gene-based association analysis, transcriptome-wide association studies (TWAS), and prote...

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Literature Corpus work: c7140454-b1fa-5eeb-9fff-3bcfd127ca57
DOI: 10.64898/2026.04.10.26350571

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