Article

Proteomic and genetic insights into ancestry-specific associations in Parkinson’s disease

2025-06-06

Abstract excerpt

<h4>ABSTRACT</h4> Genome-wide association studies of Parkinson’s disease (PD) have identified multiple genetic variants across populations, but the biological mechanisms remain largely unknown. To investigate ancestry-specific disease pathways, we performed a series of Mendelian randomisation analyses, integrating GWAS results with ancestry-specific protein quantitative trait loci data. For Europeans, we utilised...

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Literature Corpus work: 077913ad-9734-5e86-be95-14ffdd83878a
DOI: 10.1101/2025.06.04.25329006

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