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Article

Development of the Theta Comparative Cell Scoring Method to Quantify Diverse Phenotypic Responses Between Distinct Cell Types.

Assay and drug development technologies - 1 Sept 2016

Warchal Scott J, Dawson John C, Carragher Neil O

Abstract excerpt

In this article, we have developed novel data visualization tools and a Theta comparative cell scoring (TCCS) method, which supports high-throughput in vitro pharmacogenomic studies across diverse cellular phenotypes measured by multiparametric high-content analysis. The TCCS method provides a univariate descriptor of divergent compound-induced phenotypic responses between distinct cell types, which can be used...

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Identifiers

PMID: 27552144
DOI: 10.1089/adt.2016.730
PMCID: PMC5015429

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