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Article

Relevance of Clonal Hematopoiesis in Immune Cells for Degenerative Aortic Valve Stenosis.

Journal of the American Heart Association - 17 Mar 2026

Mas-Peiro Silvia, Dimmeler Stefanie, Zeiher Andreas M

Abstract excerpt

Clonal hematopoiesis of indeterminate potential (CHIP), defined as the presence of somatic mutations in subjects without other hematologic abnormalities has been recently associated with several cardiovascular diseases. Degenerative aortic valve stenosis (AVS), a prototypical cardiovascular age-related disorder resulting from calcification and inflammation processes for which no medical treatment is currently...

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Source

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Identifiers

PMID: 41294132
DOI: 10.1161/JAHA.125.044406
PMCID: PMC13055804

Genes

DNMT3A
TET2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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