Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Nonpreferential but Detrimental Accumulation of Macrophages With Clonal Hematopoiesis-Driver Mutations in Cardiovascular Tissues-Brief Report.

Arteriosclerosis, thrombosis, and vascular biology - 1 Mar 2024

Dederichs Tsai-Sang, Yerdenova Assel, Horstmann Hauke, Vico Tamara Antonela, Nübling Simone, Peyronnet Rémi, Pfeifer Dietmar, von Zur Muehlen Constantin, Heidt Timo, Wolf Dennis, Czerny Martin, Westermann Dirk, Hilgendorf Ingo

Abstract excerpt

BACKGROUND: Clonal hematopoiesis of indeterminate potential (CHIP) is an acquired genetic risk factor for both leukemia and cardiovascular disease. It results in proinflammatory myeloid cells in the bone marrow and blood; however, how these cells behave in the cardiovascular tissue remains unclear. Our study aimed at investigating whether CHIP-mutated macrophages accumulate preferentially in cardiovascular...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cardiovascular Diseases
Share to Clonal Hematopoiesis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Hematopoiesis

Share to Macrophages

Share to Mutation

Source

Open in PubMed Open full text

Identifiers

PMID: 38269586
DOI: 10.1161/ATVBAHA.123.320183
PMCID: PMC10880934

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Nonpreferential but Detrimental Accumulation of Macrophages With Clonal Hematopoiesis-Driver Mutations in Cardiovascular Tissues-Brief Report.PMID 38269586Read ↗

Non-preferential, but detrimental accumulation of macrophages with clonal hematopoiesis-driver mutations in cardiovascular tissuesSemantic proximity Read ↗

Clonal hematopoiesis driven by DNMT3A and TET2 mutations: role in monocyte and macrophage biology and atherosclerotic cardiovascular disease.Semantic proximity Read ↗

Leukocytes carrying<i>Clonal Hematopoiesis of Indeterminate Potential</i>(CHIP) Mutations invade Human Atherosclerotic PlaquesSemantic proximity Read ↗

Loss-of-function mutations in Dnmt3a and Tet2 lead to accelerated atherosclerosis and concordant macrophage phenotypes.Semantic proximity Read ↗

CHIP In cardiovascular and immune ageing.Semantic proximity Read ↗

Clonal hematopoiesis of indeterminate potential (CHIP): Linking somatic mutations, hematopoiesis, chronic inflammation and cardiovascular disease.Semantic proximity Read ↗

Common clonal hematopoiesis driver mutations have disparate effects on macrophage cytokines, clonal expansion, and atherogenesis.Semantic proximity Read ↗

<i>TP53-</i> mediated clonal hematopoiesis confers increased risk for incident peripheral artery diseaseSemantic proximity Read ↗

TET2-CHIP: From Mutation to Malady.Semantic proximity Read ↗

Clonal Hematopoiesis and Risk of Atherosclerotic Cardiovascular Disease.Semantic proximity Read ↗

Clonal haematopoiesis of indeterminate potential and mortality in coronary artery disease.Semantic proximity Read ↗

Clonal hematopoiesis and atherosclerosis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.