Article
A feedback loop: Interactions between Inflammatory Signals and Clonal Hematopoiesis in Cardiovascular Disease.
Molecular biology reports - 1 Apr 2021
Li Jiashan, Wang Chao, Liu Jiaru, Yu Ying, Liu Yuee, Peng Qi, Liu Huihui, Guan Xiuru
Abstract excerpt
Age and inflammation are powerful drivers of cardiovascular disease. With the growing recognition that traditional cardiovascular risk factors are not fully accurate predictors of cardiovascular disease, recent studies have revealed the prevalence of positive selection of somatic cell mutations in hematopoietic stem cells in the elderly population, which can cause clonal hematopoiesis. Interestingly, clonal...
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