Article
Association of Clonal Hematopoiesis of Indeterminate Potential With Inflammatory Gene Expression in Patients With Severe Degenerative Aortic Valve Stenosis or Chronic Postischemic Heart Failure.
JAMA cardiology - 1 Oct 2020
Abplanalp Wesley Tyler, Mas-Peiro Silvia, Cremer Sebastian, John David, Dimmeler Stefanie, Zeiher Andreas M
Abstract excerpt
Importance: Cytokine release syndrome is a complication of coronavirus disease 2019. Clinically, advanced age and cardiovascular comorbidities are the most important risk factors. Objective: To determine whether clonal hematopoiesis of indeterminate potential (CHIP), an age-associated condition with excess cardiovascular risk defined as the presence of an expanded, mutated somatic blood cell clone in persons...
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