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Article

TP53 c.730G > A pathogenic variant as a plausible candidate biomarker in pancreatic ductal adenocarcinoma patients from Karachi, pakistan: a retrospective cohort study.

BMC cancer - 7 Nov 2025

Ali S M Adnan, Adnan Yumna, Ali Saleema Mehboob, Ahmad Zubair, Azam Iqbal, Chawla Tabish, Farooqui Hasnain Ahmed

Abstract excerpt

BACKGROUND: Pancreatic cancers is known to stand among the most aggressive cancers with low survival rate. Research indicates that investigating target biomarkers can provide scientific grounds for tailored treatments in cancers. However, biomarker expression is observed to vary among different populations. Therefore, investigating the population biomarkers is a pre-requisite to understand the disease patterns...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Carcinoma, Pancreatic Ductal

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Source

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Identifiers

PMID: 41204213
DOI: 10.1186/s12885-025-15057-0
PMCID: PMC12595659

Genes

TP53
KRAS
APC
BRCA1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

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