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Article

Germline genetic profiling utilizing multigene panel testing in Jordanian patients with pancreatic cancer: a comprehensive cancer center experience.

BMC cancer - 10 Feb 2026

Abdel-Razeq Hikmat, Saleh Yacob, Hani Hira Bani, Abdel-Razeq Rashid, Mohamad Issa, Sharaf Baha, Tamimi Faris, Abu-Jaish Hala, Al-Atary Areej, Aljabri Anisa, Alnajjar Rahaf, Sammour Mohammd, Ghanem Ameed, Amarin Rula, Awabdeh Tala

Abstract excerpt

BACKGROUND: Pancreatic ductal adenocarcinoma (PDAC) is a leading cause of cancer-related deaths worldwide. Between 5% and 10% of PDACs are attributable to inherited genetic alterations, identification of which may enhance targeted screening and inform treatment decisions. Data on germline variants among Arab patients with PDAC are lacking. METHODS: This prospective study included adult patients with PDAC treated...

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Source

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Identifiers

PMID: 41668007
DOI: 10.1186/s12885-026-15669-0
PMCID: PMC13005315

Genes

APC
ATM
BRCA1
BRCA2
CFTR
CHEK2
MGP
MSH6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

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